King's College University of London

Post Doctoral Researcher
Randall Division of Cell and Molecular
Biophysics / Structural Biology Section

Università degli Studi di Catania

University of Medicine of Catania
Biomedical Sciences Department
General Pathology and Experimental
Oncology Section

Università degli Studi di Catania

Post Graduate Master
University "La Sapienza" of Rome
Biosapiens Network of Excellence


- Structural Biology
- Computational Onco-Proteomics
- Human Genome Evolution



Ph.D. in “Clinical, Experimental and Computational Pathology and Hematology”, University of Medicine of Catania (Italy) - Department of Biomedical Sciences. Project title: Computational and experimental validation of the mechanisms regulating BCR intracellular localization. Supervisors: Prof. Angelo Messina and Dr. Paolo Vigneri.


B. Sc. habilitation achieved at the University of Catania (Italy).


Post graduate Master course in Bioinformatics. University "La Sapienza" of Rome (Italy) with final grade of 110/110 cum laude. Thesis title: In Silico analysis of bacterial NRPSs stored domain in eukariotic genomes. This Master participates to the initiative of the Biosapiens Network of Excellence for the coordination of the European Master. Supervisor: Prof. Anna Tramontano.

Member of the Bioinformatics Italian Society - (BITS)

Member of the Italian Society of Biochemistry and Molecular Biology - (SIB)


Degree in Biological Sciences (5 years program equivalent to Master of Science including 2 years research in Molecular Biology). University of Catania (Italy) with final grade of 110/110 cum laude. Thesis title: Cloning and trans-activation of the SURVIVIN gene's promoter. Supervisor: Prof. Angelo Messina.



A.I.R.C. / Marie Curie Action International Fellowship in Cancer Research (two years fellow) for the project: Biocomputational and Structural Characterization of the Mechanisms leading to Imatinib resistance in Chronic Myeloid Leukemia(CML)


G. Musumeci, R. Imbesi, F. Maria Trovato, M. Anna Szychlinska, F. Concetta Aiello, P. Buffa, P. Castrogiovanni
Importance of serotonin (5-HT) and its precursor L-tryptophan for homeostasis and function of skeletal muscle in rats. A morphological and endocrinological study.
Acta histochemica 2015

M. Massimino, M. Consoli, M. Mesuraca, F. Stagno, E. Tirrò, S. Stella, M. S. Pennisi, C. Romano, P. Buffa, G. Morrone, F. Di Raimondo, L. Manzella, P. Vigneri
IRF5 is a Target of BCR-ABL Kinase Activity and Reduces CML Cell Proliferation.
Carcinogenesis Journal 2014

P. Buffa, C. Romano, A. Pandini, L. Manzella, F. Fraternali, P. Vigneri
BCRABL Residues Interacting with Ponatinib are Critical to Preserve the Tumorigenic Potential of the Oncoprotein.
The FASEB Journal 2013

D. Aliotta, P. Buffa, G. Iaccarino
An Evolutionary General Purpose WebGIS to Disclose EGFR Mutations in Lung Cancer.
Lecture Notes in Computer Science LNCS, Springer-Verlag Berlin Heidelberg 2008

P. Buffa, L. Manzella, M.L. Consoli, A. Messina, P. Vigneri
Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded.
Proteins: Structure, Function, and Bioinformatics 2007

C. Di Pietro, M. Ragusa, L. Duro, M.R. Guglielmino, D. Barbagallo, A. Carnemolla, A. Laganà, P. Buffa, R. Angelica, A. Rinaldi, M.S. Calafato, I. Milicia, C. Caserta, R. Giugno, A. Pulvirenti, V. Giunta, A. Rapisarda, V. Di Pietro, A. Grillo, A. Messina, A. Ferro, K.H. Grzeschik, M. Purrello
Genomics, Evolution and Expression of TBPL2, a member of the TBP family.
DNA and Cell Biology 2007

Author of “Sistemi Linux in Bioinformatica”, published by LinuxPro magazine, Future Media Italy - Milan, November 2004


Italian Society of Pathology in collaboration with the American Society for Investigative Pathology
XXIX National Congress - University of Calabria - Rende (Italy) 10-13/09/2008
P. Buffa, M. Massimino, A. Fidilio, L. Manzella, A. Messina, P. Vigneri
Computational and biological characterization of nuclear import / export signals of the human BCR protein. [Poster Section ST03 - PDF]

10th International Conference on Visual Information Systems (VISUAL08) - Salerno (Italy) 11-12/09/2008
D. Aliotta, P. Buffa, G. Iaccarino.
An Evolutionary General Purpose WebGIS to Disclose EGFR Mutations in Lung Cancer.
Lecture Notes in Computer Science LNCS 2008, Springer-Verlag Berlin Heidelberg Vol. 5188 pp.247-258.

Conference CNB9 - Biotechnology Fondation - Turin (Italy) 7-9/09/2006
M.L. Consoli, P. Buffa, L. Manzella, A. Messina, P. Vigneri.
Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded. [Poster Section - PDF]



Bioinformatics teaching Activity at the Faculty of Medicine of the University of Catania and Public Speacker in several schools on behalf of the Associazione Italiana Ricerca sul Cancro (AIRC) on cancer prevention and molecular therapeutics.


Responsible for the 1st course of "Bioinformatics Operator on GNU/Linux System" organized by Ephestus Linux Solution - Catania (Italy).


Tutor at the 3th course International School of Advanced Biomedicine and Bioinformatics - Lipari (Italy) and presentation on the theme: "Natively Unfolded Proteins".


Knowledge of English language and technical-scientific English


I play chess at a competitive level [ Terza Nazionale Federazione Scacchistica Italiana ( FSI ) ].

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